The drug is resorbed in the stomach testosterone propionate cycle and intestines. Maximum plasma concentration of the drug after oral administration is 1-3 hours. Contact cinnarizine plasma protein is 91%. Completely metabolized in the liver (by glyukuronirovaniya).
Displays in the form of metabolites: 1/3 – 2/3 and kidneys – intestines.
Therapeutic indications Adults Treatment of cerebrovascular origin symptoms (dizziness, tinnitus, headache vascular genesis, irritability, impaired memory and concentration), vestibular disorders (including Meniere’s disease, vertigo, tinnitus, nystagmus, nausea and vomiting labyrinthine origin), prevention kinetoses ( “road of disease” – sea and air sickness), migraine (prevention of attacks); peripheral circulatory disorders ( “intermittent” claudication, Raynaud’s disease, diabetic angiopathy, thrombophlebitis, trophic disorders (including trophic and varicose ulcers), akrotsianoz, paresthesia, nocturnal cramps and cooling in the limbs). Children older than 5 years Prevention kinetoses ( “traffic’s disease” – sea and air sickness)
Hypersensitivity, pregnancy, lactation.
Age 5 years (effectiveness and safety have been established).
In Parkinson’s disease.
Pregnancy and lactation
Although pre-clinical studies testosterone propionate cycle have not revealed teratogenic effects of cinnarizine, the drug can be assigned during pregnancy only if the expected benefit to the mother outweighs the potential risk to the fetus.
There are no data on the penetration of cinnarizine in mother’s milk, so in while receiving breastfeeding drug should be discontinued.
Dosing and Administration
Inside, after a meal.
If you violate the circulation of the brain – 25-50 mg (1-2 tablets) three times a day; in violation of the peripheral circulation – at 50-75 mg (2-3 tablets) three times a day; during vestibular disorders – 25 mg three times a day; when kinetoses ( “Road” disease): adults – 25 mg half an hour before the trip (if necessary repeated reception of 25 mg every 6 hours). The maximum dose should not exceed 225 mg (9 tablets) per day. The dose for children aged 5 to 12 years – 14 doses, the recommended adult dose for children over 12 years corresponds to the dose recommended for adult patients.
With a high sensitivity to the drug treatment is initiated with half the dose, increasing it gradually. The course of treatment from a few weeks to several months.
Interaction with other drugs
increases the effects of alcohol and sedatives, tricyclic antidepressants.
In an application with nootropic, antihypertensive and vasodilator enhances their effect, while the use of drugs prescribed for hypotension – reduces their effect.
Side effect On the part of the nervous testosterone propionate cycle system: drowsiness, fatigue, headache, extrapyramidal disorders (tremor of the limbs and increased muscle tone, hypokinesia elderly patients in long-term treatment, in such cases, treatment should be discontinued), depression. From the digestive system: dry mouth, epigastric pain, dyspepsia, cholestatic jaundice (extremely rare). For the skin: sweating, development volchanochnopodobnogo syndrome, lichen planus (extremely rare), skin rash. Other: Allergic reactions, increased body mass index. men’s health